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Gliomatosis Cerebri on the News

NCI: Updates of the Understanding of Gliomatosis Cerebri 

Gliomatosis cerebri is diagnosed based on imaging, instead of pathology like most other tumor types. It occurs most often in people between the ages of 46 and 53 but can occur at any age. Gliomatosis cerebri occurs slightly more often in males than females. It usually appears abnormal in three or more lobes of the brain. To understand it better clinicians grouped it into three grades based on their characteristics.

GliomatosisCerebri: Current Understanding and Controversies

Gliomatosis cerebri (GC) is a rare, extensively infiltrating glioma involving multiple contiguous lobes of the brain. This lethal disease affects all age groups, and the majority of patients have a poor outcome despite aggressive treatment. Despite its initial recognition in 1938, GC remains a controversial entity with little consensus in its definition, histology, or treatment. The majority of GC tumors are astrocytic, although mixed phenotypes have been identified.

Brain Tumor Advancement Researches

Dr. Souweidane’s Phase 1 Trial Findings

The long-anticipated research of Dr. Mark Souweidane’s Phase 1 Trial is finally Published in Lancet Oncology in June 2018. The outcome now leads to a greater hope for the finding of the cure. Dr. Suoweidane was ever thankful to all the research supporters which are mostly foundations and cancer institutions. The study was conducted purposely to evaluate the safety of the proposed convection-enhanced delivery of a radioimmunotherapy agent targeting the glioma-associated B7-H3 antigen in children with diffuse intrinsic pontine glioma.
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